影响噪声性听力损伤药物治疗效果的相关因素分析.docVIP

影响噪声性听力损伤药物治疗效果的相关因素分析 刘昌荣徐世伦金剑明 湖南省怀化市第二人民医院靖州医院耳鼻咽喉科 湖南怀化418400 目的研究分析影响药物治疗噪声性听力损伤疗效的相关因素，并分 析相关对策。方法选取2009年1月~2012年1月间入院治疗的噪声性听力损 伤患者166例，采用相同的药物治疗方案治疗后，根据疗效的结果将其分为有效 组和无效组，对两组患者的临床资料进行分析，采用单因素和多因素Logistic逐 步回归对影响患者临床疗效的因素进行分析。结果166例患者经治疗后，78 例患者听力改善判定为有效，88例为无效。将两组患者的临床资料经单因素和 多因素Logistic逐步回归分析得知，噪声强度、噪声环境中所处的时间、听力阈 值、重金属暴露、粉尘暴露为影响药物治疗噪声性听力损伤疗效的独立因素。结 论噪声性听力损伤属综合性损伤，采用药物治疗的临床疗效不是非常满意，及 早诊断及早治疗，加强预防以降低噪声性听力损伤的发牛。 关键词噪声性听力损伤；药物治疗；影响疗效因素 [Abstract]Ojective to study the in flue nee of noise an alysis drug treatme nt the curative effect of hearing impairment related factors, and analyzes related court termeasures.Methods choose from Jan uary 2009 to 1 month of noise to the hospital for treatment of 166 cases of patients with hearing impairment, use the same drug treatment after treatment, according to the result of curative effect which is divided into effective group and invalid group, two groups of patients in the clinical material carries on the analysis, the single factor and multiple factors Logistic stepwise regression to in flue nee the clin ical curative effect of the factor to carry on the analysis.Results 166 patients after treatment, 78 patients to improve listening to determine effective, 88 cases of invalid.The two groups of patients with clinical data by single factor and multiple factors Logistic stepwise regression analysis that the noise intensity, noise environment in time, hearing threshold, heavy metal exposure, dust exposure to affect drug treatment noise of hearing impairment curative effect of in dependent factors.C on clusio n the noise of heari ng loss which is a comprehensive damage, the drug treatment of clinical curative effect is not very satisfactory, early diagnosis, early treatme nt to st re ng the n preve ntion to reduce noise sex heari ng damage occurs. [Key words]noise of hearing impairment； Drug therapy； Affect curative effect factors 噪声性听力损伤是指患者因暴露在噪声环境下所引起的渐进性感咅神经性 耳聋，并且无论是一次锻造的强脉冲噪声或长期反复呃噪声暴露所致的听力下降 [l]o近年来，由于我国工业化进程的加快，人们生活处于