沙门氏菌外膜蛋白的分析-免疫学专业论文.docxVIP

硕士研究生学位论文·中国食品药品检定研究院·201 硕士研究生学位论文·中国食品药品检定研究院·2010 级 PAGE PAGE 2 Abstract Salmonella, Gram-negative bacteria ，can cause zoonotic disease. Salmonella outer membrane protein can induce macrophage apoptosis, bacterial resistant, and as a virulent factor plays an important role in the pathogenesis. The distributions of btuB, mipA, nmpC, pagC were studied and outer membrane protein BtuB, MipA, NmpC, PagC immunogenicity was detected. The function of Salmonella typhimurium gene mipA was evaluated by deletion this gene. Firstly, the distributions of btuB, mipA, nmpC, pagC were studied. Our labora