课件：组织与胚胎学双语骨与软骨.ppt

B. Osteoblast(成骨细胞) Location: at surface of bone tissue in a layer; LM: cuboidal, low columnar, polygonal strong basophilic, large pale nuclear w/ obvious nucleolus EM: short processes gap junctions; rich in rER Gl. Osteoblast release matrix vesicle Osteoid Ca++ bone matrix Osteoblasts osteocytes osteoblast fibers g.s osteoid (类骨质) Function: C. Osteocyte (骨细胞) Location: embedded in calcified matrix LM: cell body: Flat ovoid, in lacunae; processes: long fine, in canaliculi weak basophilic tissue fluid fills in bone lacunae(骨陷窝) bone canaliculi(骨小管) EM: gap junction b/w connected processes for intercellular communication Function: Maintain renew the bone matrix; Exchange the Ca 2+ b/w tissue fluid and blood processes Osteoclast(破骨细胞) Location: In depression on the bone surface termed Howship’s lacunae LM: Giant cell, irregular, multinucleate (5-50), fusion of monocytes), acidophilic, ruffled border(皱褶缘) EM: Mv.(ruffled border); ring clear zone(w/ Mf.) Lysosomes; Phagocytosis vacuoles Others: Mit. rER. THANK YOU SUCCESS * * 可编辑 Function: Clear zone(亮区): attached the bone surface to form a microenvironment Osteoclasts release lysosomal enzymes (proteinases, carbonic anhydrase), acids (citric acid, lactic acid) to dissolve the bone matrix Mv.: increase the absorptive area absorb the dissolved products * belong to the mononuclear phagocyte system 4. Bone structure long bone diaphysis (骨干 ) (compact bone) epiphyses ( 骨骺 ) (sponge bone) A. Spongy bone(松质骨) Location: at the end inner surface of a long bone Structure: Parallel lamellae trabeculae osteocytes spongy-like network. The canaliculi open to the marrow cavity B. Compact bone(密质骨) Circumferential lamellae(环骨板) Osteon