地佐辛预防全身麻醉苏醒期患者躁动的临床观察.docxVIP

地佐辛预防全身麻醉苏醒期患者躁动的临床观察 段锦玉尚红梅郭晓雨 (陕西省榆林市第四医院陕西榆林719000) 【摘 要】目的：观察地佐辛预防全身麻醉苏醒期患者躁动的效果。方法：选 取木院收治的78例ASA 1或II级全身麻醉下行择期腹腔镜手术患者为研究对象, 随机分为对照组与地佐辛组，每组39例。患者手术结束前30min,地佐辛组静 脉注射地佐辛5mg,对照组静脉注射等量的牛理盐水。观察两组患者躁动的发牛 情况，患者的呼吸恢复时间、睁眼时间以及拔管时间以及不良反应等。结果：地 佐辛组的躁动评分明显优于对照组，两组相比，差异有统计学意义(Plt;0.05)o 地佐辛组和对照组患者的呼吸恢复时间、睁眼时间以及拔管时间和不良反应发牛 率相比，差异无统计学意义。结论：地佐辛可有效预防全身麻醉苏醒期躁动的发 生，且安全可靠，值得临床推广。 【关键词】地佐辛；全身麻醉；苏醒期躁动 【中图分类号1R614.2 【文献标识码】B 【文章编号11003-5028(2015 ) 6-0479-02 Clinical Effect of Dezocine in Prevention of Restlessness during Anesthesia [Abstract] Objective： Observation of clinical effect of dezocine in prevention of restlessness during anesthesia. Methods： 78 cases of ASA I or II patients un dergoi ng elective gyn ecological laparoscopy under sevoflura ne gen eral an esthesia were randomly divided into 2 groups with 39 cases each. Group Dezocine received dezocine 5 mg 30 min before the end of operation, Group Control received equal volume of normal saline. The occurrenee of agitation was observed during waking-up period. Agitation scale; from the withdrawal to patients awake time; respiratory depression, nausea and vomiting dizziness, skin itching and other related adverse reaction after extubation were observed. Results： In group Dezocine, patients emergence agitation rate was significantly lower than that in group Control ( P 0.05), respiratory depression, constipation, itching and other adverse reactions between the 2 groups had no significant differenee. Conclusion： Received iv dezocine before the end of operation can effectively prevent the occurrenee of agitation duri ng waki ng-up period of sevoflura ne gen eral an esthesia after gyn ecological laparoscopy. 【Key words] Dezocine; General anesthesia; Postoperative agitation 全身麻醉苏醒期患者躁动⑴是麻醉苏醒期的一种不适当行为，其具体表现 为⑵语无伦次、肢体的无意识动作、哭喊或呻吟、无理性言语、妄想思维等， 这些全身麻醉手术后的躁动挣扎、兴奋等现象增加了苏醒期的风险。如果处理不 适当，将危及患者生命。本研究观察使用地佐辛预防全身麻醉苏醒期患者躁动的 效果，旨在为全身麻醉苏醒期躁动的药物预防研究提供理论依据。 1资料与方法 1.1研究对象 选取来我院进行治疗的ASA I或II级全身麻醉下行择期腹腔镜手术患者78 例作为研究对象。其中男42例，女36例，年龄16?78岁，平均年龄(43.2