睾丸酮丛毛单胞菌临床分布及耐药性分析.docVIP

睾丸酮丛毛单胞菌临床分布及耐药性分析 孔昌盛1，陈俊2，邹晓艳1，张义1，朱玲娜1 （1：湖北省宜昌市夷陵医院检验科，湖北 宜昌443100；2：三峡大学仁和医院手外科，湖北 宜昌443001） 作者简介：孔昌盛，男，检验技师，本科，从事微生物学检验，E-mail： kcs1018@163.com 电话摘要：目的 了解睾丸酮丛毛单胞菌在临床标本中的分布及耐药性，为临床治疗提供依据。方法 对我院2013年7月-2014年12月临床分离的睾丸酮丛毛单胞菌引起的感染分布及药敏结果进行回顾性分析。结果 2年各种标本中共分离培养出睾丸酮丛毛单胞菌23株，标本全部来源于阑尾脓液和腹腔分泌物，分别占91.3%和8.7%；感染全部发生在普外科病区和ICU病区，分别占95.7%和4.3%；睾丸酮丛毛单胞菌对哌拉西林耐药率最高，为21.7%，而对替卡西林、替卡西林/克拉维酸、哌拉西林/他唑巴坦、头孢吡肟、亚胺培南、美洛培南、头孢他啶、阿米卡星、庆大霉素、妥布霉素、环丙沙星、复方新诺明敏感率高达100%。结论 我院检出的睾丸酮丛毛单胞菌对各种抗菌药物均比较敏感，应规范抗菌药物的临床应用，减少耐药性菌株产生及扩散。 关键词：睾丸酮丛毛单胞菌；耐药性；临床分布 Clinical distribution and drug resistance of Comamonas testosterone causing infections KONG Chang-sheng1,CHEN Jun2,ZOU Xiao-yan1,ZHANG Yi1,ZHU Ling-na1 (1:Department of Clinical Laboratory,Yiling Hospital of Yichang City,Hubei Province,Yichang 443100;2:Hand surgery,The Renhe Hospital of Sanxia University,Yichang 443001,China) Abstract: OBJECTIVE To understand distribution of Comamonas testosterone in the clinical specimens and analyze the drug resistance so as to guide the clinical treatment.METHODS From Jul 2013 to Dec 2014 ,the distribution of clinical isolates of C.testosterone and the result of drug susceptibility testing were retrospectively analyzed.RESULTS A total of 23 strains of C.testosterone have been isolated from various specimens obtained during the 2 years,91.3% of which were isolated from the appendix pus,8.7% from abdominal secretions;The patients with infections in the department of general surgery accounted for 95.7%,and the patients with infections in the ICUs accounted for 4.3%;The drug resistance rate of the C.testosterone to piperacillin was the highest(21.7%),The sensitive rate to Ticarcillin, Ticarcillin/Clavulanic acid,Piperacillin/tazobactam,Cefepime,Imipenem, Meropenem,Ceftazidime,Amikacin,Gentamicin,Tobramycin,Ciprofloxacin, Paediatric Compound Sulfamethoxazole Tablets whereas as 100%.CONCLUSION The research in our hospital finds the C.testosterone strains are sensitive to various antibiotics,so th