化学化工类专业英语11-13课件.pptVIP

Classification of potential scaffold materials Bioinert: no toxic response from the body on implantation. Usually results in fibrous encapsulation (scar tissue formation). Bioresorbable: undergoes degradation in the body. Dissolution products are harmless and can be secreted naturally. Bioactive: Produces a biological response from the body that results in a bond between the material and the host tissue. Biomaterials: Examples Joint replacements Bone plates Bone cement Hip Joint Artificial ligaments and tendons Dental implants for tooth fixation Blood vessel prostheses Heart valves Skin repair devices Cochlear replacements Contact lenses Hip joint Heart valve Knee joint Skin Bioreactor system Scaffold Biopsy mechanical stimuli electrical stimuli chemical stimuli Human Cell Suspension Nutrients, Growth Factors Implantation operation H Biomaterials Scaffolds for tissue engineering Polyurethane scaffolds made by particulate leaching Composite (polymer/ceramic) scaffold made by rapid prototyping method FE models of the scaffold-new bone) Bone Tissue Engineering Modeling in Tissue Engineering Biomaterials Ceramic-polymer composites for dental fillings reduction of polymerisation shrinkage improvement of wear resistance improvement of mechanical properties nano-composites * * * * Thermoplastic - material form/shape can be manipulate by heating. Shape is retained upon cooling. Process can be repeated. Ex: Plastic silverware, CD’s, CD cases, Clothing, Frisbee Thermosets: material form/shape can be only changed once. Usually accompanied with a catalyst such as heat, light or chemical. Process is not repeatable. Ex: Bowling Ball, Corvette body, Tennis Racket, Golf Shaft Light switch Rubber: A subset of thermosets. Process includes both vulcanization with suflur and more modern cross linking agents. Rubber tires, soles of shoes/sneakers, tennis balls, golf balls Elastomers: A softer rubber with higher elongations, I.e. better elasticit