《咪唑三嗪化合物的合成研究》-毕业论文（设计）.docVIP

本科毕业论文 × 咪唑三嗪化合物的合成研究 × 专 业 化学工程与工艺 学生姓名 班 级 BD化工091 学 号 0920301101 指导教师 完成日期 2013年06月19号 盐城工学院本科毕业论文 PAGE ii PAGE I × 咪唑三嗪化合物的合成研究 × 摘 要：本文主要阐述了葡醛内酯的性质、应用、研究进展及发展趋势，研究了以淀粉为原料，经氧化，水解，内酯化制取葡醛内酯的合成方法。在合成葡醛内酯的实验过程中，考察了反应温度、反应时间、加料速度等因素对反应收率的影响，探寻了合成葡醛内酯的最佳工艺条件：100g淀粉中加入70ml发烟硝酸和30ml的水，温度在50℃左右，且淀粉加入的速度应适当，反应时间为2小时，浓缩水解液时温度应控制在55℃以下，内酯化反应中加入醋酸酐不会对葡醛内酯的产率产生影响。葡醛内酯在低温条件下能结晶析出。 关键词：葡醛内酯；氧化；水解；内酯化。 × The synthesize research on glucuronolactone × Abstract: In this paper the properties, application, the research progress and trend of D-glucuronolactone was summarized. Starch which is used as raw material can be processed into glucuronolactone by synthesis, hydrolysis and lactonization in this method. In the synthetic experiment of glucuronolactone, some factors which work on the yield such as temperature, time, the accession speed of starch were investigated. The optimum condition for the synthesis of glucuronolactone is as follows: 70mL fuming nitric acid and 30mL water should be added into 100g starch, the oxidative temperature is the about 50℃, and the accession speed of starch should be adequate, the oxidative experiment last for 2 hours; concentration temperature is less than 55℃. It is turned out that the addition of acetic anhydride had no effect on the output of glucuronolactone which can change into crystal and separate from water in the condition of low temperature. Key words: Glucuronolactone; Oxygenation; Hydrolyze; Lactonization. PAGE i 目 录 第一章 文献综述 ···········································································1 1.1 葡醛内酯的物理化学性质···························································1 1.2 葡醛内酯产品质量标准·······························································1 1.3 葡醛内酯的沿革··········································································2 1.4 葡醛内酯的药理作用和生理功能···············································2 1.5 葡醛内酯在其他领域的应用·······················································2 1.6 葡醛内酯的生产状况及市场前景·········