化疗药物配制指南.docVIP

化疗药配备 Common Antineoplastic Drug Pharmacy Preparation Chart Generic Name(INN) Trade Name Concentration /Diluent Precautions /Stock SolutionStability Vehicle forInfusion Precautions /Ready-to-UseSolutionStability Amifostine Ethyol 500 mg in 9.7mL of 0.9% NaCl 6 hrs (RT)24 hrs(refrigerated) n.r. Administerwithin 25 minutes Asparaginase Asparaginase 10,000 U in 4mL of WFI In the dark,6 hrs) 5% Dex / 0.9% NaCl ? Azathioprine Imurek 50 mg in 5-15mL of WFI 120 hrs (RTor refrigerated) 0.9% NaCl or 0.18% NaCl + 4% Dex Administer after preparation Bleomycin Bleomycin ? Numerous incompatibilities 0.9% NaCl ? Carboplatin Carboplat 50 mg in 5 mL In the dark 5% Dex / 0.9% NaCl Conc 0.5 mg/mL 8 hrs (RT) 24 hrs (refrigerated) Carmustine(BCNU) Carmubris Dissolve in 3 mL of ethanol, add 27 mL of WFI100 mg in 30 mL 5% Dex / 0.9% NaCl 0.9% NaCl 8 hrs (RT)24 hrs (refrigerated) Cisplatin Platinex 50 mg in 100 mL In the dark, RT 0.9% NaCl 8 hrs (RT) Cladribine Leustatin 10 mg in 10 mL ? 0.9% NaCl Administer within 8 hrs (refrigerated) Cyclophosphamide Endoxan 1,000 mg in 50 mL of WFI 24 hrs (refrigerated) 5% Dex / 0.9% NaCl ? Cytarabine Alexan 100 mg in 5 mL ? 5% Dex / 0.9% NaCl ? Dacarbazine(DTIC) Detimedac 100 mg in 10 mL of WFI In the dark; prepare immediately before use 5% Dex / 0.9% NaCl Administer within 30 min Dactinomycin Lyovac-Cosmogen Dissolve in 1.1 mL of WFI 0.5 mg in 1 mL In the dark 5% Dex / 0.9% NaCl ? Daunorubicin Daunoblastin 100 mg in 10 mL of WFI In the dark, 24 hrs (RT), 48 hrs (refrigerated) ? ? Docetaxel Taxotere 80 mg in 8 mL Prepare immediately before use 5% Dex / 0.9% NaCl Conc 0.74 mg/mL 4 hrs (RT) Doxorubicin(Adriamycin) Adriblastin 50 mg in 25 mL In the dark, refrigerated N/A, bolus Inject within 10-15 min Epirubicin Farmorubicin 50 mg in 25 mL In the dark, refrigerated N/A, bolus Inject within 10-15 min EstramustinePhosphate Estracyt 300 mg in 8 mL of WFI Prepare immediately before use 5% Dex NO NaCl! 12 hrs (RT)24 hrs (refrigerate