ICU应用有创呼吸机患者发生下呼吸道感染的危险因素分析.docxVIP

ICU应用有创呼吸机患者发生下呼吸道感染的危险因素分析 [Abstract] Objective To analyze the risk factors of lower respiratory tract infection in ICU patients with invasive ventilator. Methods Retrospective analysis of clinical data of 100 patients with lower respiratory tract infection from January，2014 to December 2016 in ICU of our hospital.Logistic regression analysis was carried out to investigate the influencing factors of lower respiratory tract infection. Results 100 patients with invasive ventilator，32 patients had lower respiratory tract infection with a probability of 32.0%.Eleven patients died due to ineffective treatment and the mortality rate was 34.4%.Univariate analysis showed that albumin level （P0.05），***** score，time of ventilator application，gastric contents reflux，posture， application of antacids，glucocorticoids，other invasive factors were postoperative pulmonary infection （P0.05），Ventilator application time，gastric contents regurgitation and supine position were independent risk factors for lower respiratory tract infection in patients with invasive ventilators. Conclusion The occurrence of lower respiratory tract infection in patients with invasive ventilator is related to many factors.Comprehensive treatment measures are helpful for the prevention and control of lower respiratory tract infection. [Key words] Intensive wards；Invasive ventilator；Lower respiratory tract infection；Risk factors 随着医学的发展，对于医疗质量的要求越来越高，而医院感染已经成为医院发展和提高医疗质量的重大障碍。NICU收治患者多为严重神经系统受损疾病患者，常具有基础疾病多、起病急、病情危重，常伴有意识障碍，接受侵入性操作及大量的广谱抗生素、免疫抑制剂，自身抵抗及保护能力均较差等特点决定其为医院感染的易感染群，而下呼吸道感染为其发生医院感染的最主要的类型之一[1-3]。由于部分患者发生呼吸衰竭，应用有创呼吸机的概率较高，而有创呼吸机的应用会明显增加患者下呼吸道感染的发生率。本研究对可能诱导重症监护病房当中应用有创呼吸机患者发生下呼吸道感染疾病的各种影响因素进行分析。 1 资料与方法 1.1 一般资料 选取我院在2021年1月～2021年12月收治的100在重症监护病房应用有创呼吸机患者，其中男56例，年龄2～80岁，平均（43.5±4.1）岁，女44例，年龄2～72岁，平均（44.9±3.2）岁，对所有发生下呼吸道感染疾病的患者情况进行回顾性分析，并对100例患者中引发下呼吸道的可能因素进行研究。对所有患者在整个过程中实行全方位护理，跟踪观察并记录相关数据。 1.2 方法 将所有重症监护病房应用有创呼吸机患者的临床病理资料进行整理、分類，以感染下呼吸道疾病的患者为主要研究对象，回顾性分析相关诱导因素，排除无关因素，找