2020NCCN非小细胞肺癌指南要点.docxVIP

2020NCCN非小细胞肺癌指南要点 2020年6月，美国国家综合癌症网络（NCCN ）发布了非小细胞肺癌 （NSCLC）指南2020年第6版。那么，新版指南中NSCLC精准治 疗的药物选择有哪些？ NSCLC治疗的进展情况如何？接下来，让我们 盘点部分壳点研究/ —探究竟。 以下是NCCN指南《2020.V6版》更新的要点（相较于V5版）： NationalComprehensive Cancer Network*NCCN Guidelines Version 6.2020 Non-Small Cell Lung Cancer National Comprehensive Cancer Network* NCCN Guidelines Version 6.2020 Non-Small Cell Lung Cancer UpSaW Ki Verskxn 6.2020 Of th* NCCN for Non-Smail C?a Lax^ Cancer from 5.2020 lncxto: NSCL-X) and NSCU3I1 Adtnocircinocna. large coil. NSCLC NOS: Hnrolutmb ? ipikmunub ? pemetreied ? (cartxipUtin or citptotin) adkted as an *Gthtr rtcotnmendiKr firttline treatmenc optiofi tor MitntB witti rrotatUOc NSCLC. POLI n%. and PS 0-1 S^uamout cell orctnoma: Nivolumib ? Ipilvnumob pjcMaxel ? CMbopUtin xkM ■■ in other recommwodecT ftrtfrw treMroemt opbon ■W XG4AU with AMrUUAtie MSCtC. PD4_1 n%. Md PS 0-2. NSCZ 2 2 ?xS 2 “ 2 Tb folo?wing regimen* added with rwferwncMz * ? p?nwCrrxrd (cartafHati n x ch?p4?tin) ? Nhr olumat) ? ipilimufnab ? paclitaiel ■* GirtepUtin NSCULlffiLJ ■ Adknocardnocna. cell. NSCLC MOS: Hhzolumab ■ IplUnxmab - p?m?4rvx?d ? (c^dbopUtU or cUpUta) added as an oUMr r?co?wTxnUr flr?t4irw tr?atm?ni: optiom lor ^tknU wWh nwhsUtk NSCLC. PD-L1 1%s and PS 0-1. NSCL7 J of 4 Stuanmj oil Mrcmma; Nivolvmab ? IpilmmA ? pmKak?I ? ■wrtwpIMin a an 2U?r fint-iifH optwi for RtHnm with rmrUistAtic NSCLC, PQ-L1 1%. an?d PS (M? MSCWfiU Rtftrenc ?(5aMN IfcLl Discussion. wction upd?t?d to rwfUct ttw change in tM algorfttwn. UpctatM tel VerMm S.2O2O of the NCCN GokMkwt for Non-SmaM Coll Lung Canc?r troen Wmiom 4.2020 incud?: NSCLW Atetoliiumjb added m i pewferrtd trMmnt gti“ for pMents wWh meuttMe NSCLC. PD-4.1 冷0% and PS 0-2. NSCLJ ■ and M1C1U 2 of 2 ■ Atezdizumab ?dd?d with reference. Hill DiscuMioe waion to mflect ttw Ghangra in ttw algorittvn 靶向治疗 （一）指南建议检测的靶点？ ： EGFR、ALK、ROSV BRAF、NTRK. MET、RET lAMnib1lErtotnb2OKomitinib1Giftrtb4』 lAMnib1 lErtotnb2 OKomitinib1 Giftrtb4』 OsimertinH Eriotinib * rvnudrunwb7 Erlotinib