核医学课件：PETMRI application-第4节.pptVIP

* In MRI scanning gives different Artefacts Metal artifacts are overestimated in CT and make beam hardenimg artefacts, the assessment behind the artefacts is not possible. With PET/MR using Dixon technique for AC metall artefacts are often recognized as air. If you compare Non attenuation corrected with attenuation corrected PET images you find a severe undercorrection in the corresponding region. * * An other new problem in PETMR is truncation. Due to a smaller FOV of MR compared to PET especially when imaging PET with arms down some parts of the arms (and in large patients also hips or breast) can be missing in the u-map. * * The truncation artefacts can be corrected with the mlaa-reconstruction (maximum likelihood reconstruction of attenuation and activity). On the left side we can see the μmap without the mlaa reconstruction and below the attenuation corrected PET. On the ride side we see the μmap after the mlaa reconstruction. Here, the missing parts of the arms are segmented into the image by comparing the activity of the non attenuation corrected PET with the initial u-map. The picture below is the result of the PET-AC with the mlaa reconstruction * * This wholebody images demonstrate that the quality of PET is nearly the same when comparing PET/CT and PET/MRI data sets. * Hybrid PET/MR: promising clinical applications Neurology / Neurooncology Assessment of dementia (morphology and areas of hypometabolism) Evaluation/ follow-up of brain tumors: combination of MRI and [18F]FET PET; tumor extension, DD radiation necrosis / recurrence Epileptic patients: evaluation of seizure foci Cardiovascular Applications Combination of physiological, biological and structural information Oncology Applications profiting from the excellent soft tissue contrast of MRI: SCCHN, liver imaging, breast cancer, imaging of prostate cancer Pediatric oncology: Less radiation exposure, only one anesthesia, excellent soft tissue contrast of MRI Musculo-skelettal applications (p