有关七氟醚与异丙酚用于全麻诱导的效果比较（临床医学资料）.docVIP

有关七氟醚与异丙酚用于全麻诱导的效果比较（临床医学资料） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：有关七氟醚与异丙酚用于全麻诱导的效果比较 1 1 资料与方法 2 2 结果 4 3 讨论 5 4 小结 6 文2：Narcotrend监测下七氟醚为辅佐用于老年患者全麻诱导的临床研究思路 7 2 结果 9 参考文摘引言： 11 原创性声明（模板） 12 文章致谢（模板） 13 正文 有关七氟醚与异丙酚用于全麻诱导的效果比较（临床医学资料） 文1：有关七氟醚与异丙酚用于全麻诱导的效果比较 ［Abstract］ Objective To compare the effects of induction with sevoflurane and propofol in stress reaction and Forty ASAⅠorⅡ patients aged 18～65 were randomized into 2 groups(n=20):sevoflurane group (S) and propofol group （P).In group S induced with anesthesia was started with 5% sevoflurane and fresh gas flow rate of 5 L/ ipired concentration of sevoflurane was reduced to 1 group P induced with TCI of target plasma concentration (CT)of propofol was at 3 mg/ observed the variation of blood BP，HR，blood sugar in different time in both time of loss of cociousness (LOC)was BP，blood sugar in both groups and HR in group S were significantly decreased immediately before intubation as compared with the baseline values before induction of anesthesia (P＜).BP and HR returned to the baseline levels after was significantly lower after intubation in group S than in group sugar level in group P was much higher than group S after intubation 10 min (P＜).The time of LOC was significantly shorter in group S than in group P (P＜).Conclusion Induction of anesthesia with sevoflurane can lead to less stress and minor variation in hemodynamics than injection of propofol，so it is better for anesthesia。 ［Key words］ propofol；sevoflurane；general anesthesia inducing 七氟醚是一种新型吸入全身麻醉剂，该药具有良好的麻醉性能，它血气分配系数低，对呼吸道刺激作用小，诱导期短，苏醒快，麻醉过程平稳，可以安全用于成人、儿童和老年人的麻醉。异丙酚近年来已广泛应用于临床麻醉及ICU镇静、镇痛等，取得较好的效果。本试验通过比较七氟醚吸入麻醉与异丙酚靶控输注用于LC手术麻醉诱导对患者血流动力学、应激反应、呼吸道刺激症状等的影响，观察两药的麻醉效果，为临床合理选择麻醉诱导方法提供参考。 1 资料与方法 一般资料 选择ASAⅠ级或Ⅱ级择期行LC手术患者40例，男24例，女16例，年龄18～65岁，体质量48～82 kg，术前无精神、神经疾病史，无长期阿片类或安定类用药史，无严重心、肺及中枢神经系统疾病史，肝、肾功能未见明显异常。随机分为2组，每组20例(n=20)：七氟醚组(S组)和异丙酚TCI组(P组)，两组患者一般情况无显著差异。 麻醉方法 患者入手术室前30 min肌肉注射苯巴比妥钠 g，阿托品 mg。患者入室后建立静脉通道，常规监测心电图，脉搏血氧