胰岛素及口服降糖药.pptx

胰岛素及口服降糖药;Diabetes Mellitus;Diabetes Mellitus;ADA Classification of Diabetes;第一节 胰岛素 Insulin;Charles Best (left) and Frederick Banting (right) Extracted insulin and treated dogs (1921) ;;胰岛素Insulin;Stage 1 Insulin was extracted from the glands of cows and pigs、 (1920s) Stage 2 Convert pig insulin into human insulin by removing the one amino acid that distinguishes them and replacing it with the human version、 ;Stage 3 Insert the human insulin gene into E、 coli and culture the rebinant E、coli to produce insulin (trade name = Humulin?)、 Yeast is also used to produce insulin (trade name = Novolin?) (1987)、 ;;Insulin;Diabetes Mellitus;Insulin;Mechanism of Insulin Action;Insulin; 胰岛素 — [基本特征];Insulin;;;Pre-mixed Insulin;Normal Insulin Profiles;;Insulin;第二节 口服降糖药 ;Type 2 Diabetes;;Oral Hypoglycemic Drugs磺酰脲类: ----sulfonylureas;Oral Hypoglycemic Drugs ----sulfonylureas;【作用机制】;Mechanism of Insulin Release in the Pancreas;Oral Hypoglycemic Drugs ----sulfonylureas;Oral Hypoglycemic Drugs ----sulfonylureas;Oral Hypoglycemic Drugs ----sulfonylureas;Oral Hypoglycemic Drugs ----sulfonylureas;Oral Hypoglycemic Drugs双胍类: ----biguanides;Oral Hypoglycemic Drugs ----biguanides;Oral Hypoglycemic Drugs ----biguanides;Oral Hypoglycemic Drugs ----biguanides;胰岛素增敏剂: 噻唑烷二酮类--thiazolidinediones;Oral Hypoglycemic Drugs --thiazolidinediones;感谢您的聆听！