MiR-324-5p-CUEDC2轴功能失调导致巨噬细胞功能障碍和结肠癌.pptxVIP

研究背景研究思路研究结果汇 报 内 容第二页，共十九页。 常用名词CUEDC2：CUE结构域蛋白2tumor-associated macrophages (TAMs)：肿瘤相关性巨噬细胞Colorectal cancer (CRC) ：结直肠癌ko mice 基因敲除小鼠RNA-induced silencing complex〔RISE〕:RNA诱导沉默复合体第三页，共十九页。 研究背景Colorectal cancer (CRC) is the third most common malignancy 结直肠癌是排行第三的恶性肿瘤第四页，共十九页。 研究背景It is known that intestinal inflammation is one of the major causes leading to CRC Inflammatory bowel diseases (IBDs) are inflammatory disorders of the intestinal tract, which often result in the development of colitis-associated cancer(CAC)。肠道炎症是引起炎症性肠病的主要原因，由此导致结肠炎相关性肿瘤第五页，共十九页。 研究背景Macrophages are the most