量子点核酸适配体传感器在食品安全检测中的应用.pdfVIP

第14卷第11期 食品安全质量检测学报 Vol. 14 No. 11 2023年6月 Journal of Food Safety and Quality Jun.,2023 量子点核酸适配体传感器在食品安全 检测中的应用 姜欣，叶满萍*，邓敏，陈慧芳，陈华才 （中国计量大学光学与电子科技学院，杭州310018) 摘要：食品作为维持人类生命活动的基本物质，对人们的健康有重大影响，开发简单、快捷的检测技术在 保障食品安全方面具有重大意义。量子点(quantumdots,QDs)拥有独特的发光性能，核酸适配体作为新型生 物识别分子，具有亲和力高、稳定性强及特异性强等优势。将QDs和核酸适配体结合起来构建的传感器，可 实现高灵敏、高效率及特异性检测，是一种新兴的食品安全快速检测技术。本文简述了QDs核酸适配体传 感器的检测机制，重点综述了近几年来该技术在食品中抗生素、真菌霉素、致病菌、农药残留等检测中的 应用，并分析了该技术在食品安全检测领域的挑战和前景，以期为今后研发更灵敏、更高效的核酸适配体传 感器提供新的思路。 关键词：量子点；核酸适配体；生物传感器；光谱检测；食品安全 Application of quantum dot nucleic acid aptamer sensor in food safety detection JIANG Xin, YE Man-Ping*, DENG Min, CHEN Hui-Fang, CHEN Hua-Cai (College of Optics and Electronics, China Jiliang University, Hangzhou 310018, China) ABSTRACT: As the basic material to maintain human life activities, food has a significant impact on peoples health. Developing simple and fast detection technology is of great significance in ensuring food safety. Quantum dots (QDs) have unique luminescent properties. As a new type of biological recognition molecule, nucleic acid aptamers have the advantages of high affinity, strong stability and strong specificity. The sensor constructed by combining QDs and nucleic acid aptamers can achieve high sensitivity, high efficiency and specificity detection, and is a new rapid detection technology for food safety. This paper briefly described the detection mechanism of QDs nucleic acid aptamer sensor, with a focus on the recent years applications of this technique in food safety detection, such as antibiotics, mycotoxins, patho