高效压片机对粉末直压技术的诠释.pptx

DirectCompressionappliedonhigh-performancetabletpresses高效压片机对粉末直压技术的诠释

ContentFETTECompacting——yourreliablepartnerFETTE是可以信赖的伙伴Directcompressiondifferencestogranulecompression直接压片与制粒压片的区别Compactingprocess压片工艺Directcompressionadvantagesanddifficulty直接压片的优势和难点Howtosolvethisproblem怎样处理这个问题2

DirectcompressiondifferencestotheGranulecompression直接压片与颗粒压片的区别Particlesizenothomogeneous颗粒不均匀Particlesizesmallerthangranulatedpowder 粒径不不小于制粒后的颗粒bindingproblems 粘合性问题Badcompressibility可压性差Differentdensitiespossible密度差Fillingproblemsunderhighspeedconditions 在高速旋转状态下填料不充足Badflowcharacteristic流动性差3

Compactingprocess压片工艺Underhighpressuresmallerparticlesmovetointersticesofthelargerparticles在高压片力下，小颗粒嵌入到大颗粒中Slipoffandplasticdeformationoftheprimaryandsecondaryparticles产生塑性变形Formationofnewcontactsurfaces形成新的接触表面4

Advantagesofthedirectcompression直接压片的优势Nogranulationprocessnecessary不需要制粒过程Savestimeandmoney节省时间和金钱Reducedprocessandhandlingcosts减少物料损耗，增长产品收率5

Advantagesofthedirectcompression直接压片的优势Therefore,noairdryer 无需空气干燥noaircleaner无需空气清洁noairmanagement无需空气管理Noinvestmentcostforgranulationline不需要制粒线的投资6

DryGranulesProcess干法制粒工艺SaveRMB18,000,000peryear每年节省 1800万人民币7Advantagesofthedirectcompression直接压片的优势Example实例:Powder directcompressionProcess粉末直接压片

Difficultyand problemofthedirectcompression直接压片的难点和问题Badflowcharacteristicofthepowder物料流动性差Segregation(demixing)inthefeedhopperortransportbins在料斗或上料装置中出现分层现象Difficulthandlingandcompactingofthepowder可压性差8

Difficultyandproblemofthedirectcompression直接压片的难点和问题Powderbridgesinthefeedhopperandintheproductpipes在料斗中出现架桥现象Highriskofcappingofthetablets顶裂现象Highriskofstickingduringcompressing粘冲现象Compressingprocesscanonlyrununderlowerspeedincomparisontogranulatedpowder与颗粒压片相比，压片机仅能运行较低速度9

Solutionstobadcompressibility可压性差处理方案Step1:TabletCappingbecauseofbad Compressibili