儿童哮喘诊治进展.pptVIP

Slide6.InflammationinMildAsthmaNormal:Inasubjectwithoutasthma,theepitheliumisintact;thereisnothickeningofthesubbasementmembrane,andthereisnocellularinfiltrate.1Asthma:Incontrast,inapatientwithmildasthma,thereisevidenceofgoblet-cellhyperplasiaintheepithelia-celllining.Thesubbasementmembraneisthickened,withcollagendepositioninthesubmucosalarea,andthereisacellularinfiltrate,someofwhichincludeseosinophils.1Reference:?1.BusseWW,LemanskeRFJr.NEnglJMed.2001;344:350–362.Inadditiontoconstriction(narrowing)