Ocaperidone-Standard-生命科学试剂-MCE.pdfVIP

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

Ocaperidone(Standard)

Cat.No.:HY-101094R

CASNo.:129029-23-8

分⼦式:C₂₄H₂₅FN₄O₂

分⼦量:420.48

作⽤靶点:5-HTReceptor;ReferenceStandards;DopamineReceptor

作⽤通路:GPCR/GProtein;NeuronalSignaling;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Ocaperidone(Standard)是Ocaperidone(HY-101094)的分析标准品。本产品⽤于研究及分析应⽤。

Ocaperidone是⼀种有效的安定剂，为5-HT2和多巴胺D2的拮抗剂，5-HT1A的激动剂，对5-HT2，a1-

adrenergic受体，dopamineD2，组胺H

IC50TargetKi:0.14nM(5HT2),0.46nM(a1-adrenergicreceptor),0.75nM(DopamineD2),1.6nM(HistamineH1),5.4

nM(a2-adrenergicreceptor)[1]

pEC50:7.60(h5-HT1A)[2]

pKi:8.08(h5-HT1A)[2]

REFERENCES

[1].LeysenJE,etal.Invitroandinvivoreceptorbindingandeffectsonmonoamineturnoverinratbrainregionsofthenovelantipsychotics

risperidoneandocaperidone.MolPharmacol.1992Mar;41(3):494-508.

[2].CosiC,etal.Agonist,antagonist,andinverseago