细胞周期调控系统中周期蛋白与周期蛋白依赖性激酶综述.pptx

1?Cyclin-Cdkcomplexesofthecell-cyclecontrolsystem

2?ThemajorcyclinsandCdksofvertebratesandbuddingyeast

3?Summaryofthecell-cycleregulatoryproteins

4Selectedcyclinsandcyclin-dependentkinases(CDKs)生物/蛋白名称生物/蛋白名称S.pombeVertebratesCDK(onlyone)Cdk2MidG1CDKsCDK4,CDK6Mitoticcyclin(onlyone)Cdc13LateG1andS-phaseCDKCDK2S.cerevisiaeMitoticCDKCDK1CDK(onlyone)Cdk28MidG1cyclinD-typecyclinMidG1cyclinCln3LateG1andS-phaseCDKCyclinELateG1cyclinCln1,Clin2S-phaseandmitoticcyclinCyclinAEarlyS-phasecyclinGlb5,Glb6MitoticcyclinCyclinBLateS-phasecyclinandearlymitoticcyclinGlb3,Glb4LatemitoticcyclinGlb5,Glb6

5?Anoverviewofthecell-cyclecontrolsystem

6ModelforthemechanismofactionoftwoDNA-damagecheckpointChk1:关卡激酶1；Chk2:关卡激酶2

7ModelforcontrolofentryintoanaphasebyAPC-regulateddegradationofthecohesinlinkbetweensisterchromatidsSecurin:紧固蛋白

8?有丝分裂的策略—思维导图目标两个功能完全相同的二倍体子细胞战略：两步走战术：拔河战术规则：双赢核分裂胞质分裂战术：滑轮战术规则：和谐实施：微管与发动机蛋白实施：微丝与发动机蛋白