RF03176-生命科学试剂-MCE.pdfVIP

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RF03176

Cat.No.:HY-148823

CASNo.:685123-50-6

分⼦式:C₁₃H₁₀N₄OS

分⼦量:270.31

作⽤靶点:Aquaporin

作⽤通路:MembraneTransporter/IonChannel

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性RF03176是⼀种⽔通道蛋⽩-9(AQP-9)抑制剂，对mAQP3和mAQP7也表现出中等程度的抑制作⽤。

RF03176对mAQP8没有活性[1]。

IC50TargetmAQP3mAQP7AQP9

REFERENCES

[1].JelenS,etal.Aquaporin-9proteinistheprimaryrouteofhepatocyteglyceroluptakeforglycerolgluconeogenesisinmice.JBiolChem.

2011Dec30;286(52):44319-25.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师