R-Esomeprazole-R-Omeprazole-生命科学试剂-MCE.pdfVIP

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(R)-Esomeprazole

Cat.No.:HY-Z2667

CASNo.:119141-89-8

Synonyms:(R)-Omeprazole;(+)-Omeprazole

分⼦式:C₁₇H₁₉N₃O₃S

分⼦量:345.42

作⽤靶点:CytochromeP450

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性(R)-Esomeprazole((R)-Omeprazole;(+)-Omeprazole)是⼀种具有⼝服活性的细胞⾊素P450(Cytochrome

P450)2C19、CYP3A4及CYP2C9相关代谢调节剂。(R)-Esomeprazole可⽤于消化系统疾病及化合物代谢相互

作⽤研究。

REFERENCES

[1].PippaLF,etal.Impactofobesityandroux-en-Ygastricbypassonthepharmacokineticsof(R)-and(S)-omeprazoleandintragastricpH.

CPTPharmacometricsSystPharmacol.2024Sep;13(9):1528-1541.

[2].NiwaT,MurayamaN,YamazakiH.Stereoselectivityofhumancytochromep450inmetabolicandinhibitoryactivities.CurrDrugMetab.

2011Jul;12(6):549-69.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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