重用赤芍治疗早期重症急性胰腺炎.DOCVIP

临床医学论文-重用赤芍治疗早期重症急性胰腺炎 ???????????? 作者：朱德增 魏晓 张敏 张文俊 刘岩 【摘要】? 　　［目的］探讨重用赤芍治疗早期重症急性胰腺炎的临床疗效。［方法］将符合重症急性胰腺炎诊断标准的52例患者随机分成两组，对照组24例应用常规西医治疗方法，包括：监护、禁食、胃肠减压、生长抑素、抗感染等；治疗组28例在常规治疗的基础上重用赤芍煎剂，予胃管内注入。对比两组症状（腹痛、腹胀等）、体征（压痛、反跳痛、肠鸣音）恢复正常时间，并发症发生率，死亡率，住院天数及住院费用。［结果］治疗组症状缓解时间、体征恢复正常时间与对照组比较明显缩短（P0.05)；治疗组并发症的发生率、住院天数、住院费用均低于对照组（P0.05)；两组淀粉酶恢复正常时间、转手术率、病死率比较无统计学差异。［结论］早期重用赤芍治疗重症急性胰腺炎，可尽快改善患者的症状和体征、减少并发症的发生、缩短住院时间、减少治疗费用。 【关键词】? 重症急性胰腺炎；赤芍煎剂；中西医结合 　　Abstract：［Objective］ To observe the therapeutic effect of red peony root decoction (RPRD) in treating severe acute pancreatitis (SAP).［Methods］ Fiftytwo patients with SAP were randomly divided into two groups. The control group (n=24) was treated with routine treatment (intensive care, fasting, gastrointestinal decompression, somatostatin, antibiotics). The treatment group (n=28) was treated with RPRD and routine treatment. The therapeutic effects were observed in 7 days. Signs and syndromes, complications, mortality, hospitalization period and hospital charges were observed. ［Results］ The treatment group alleviated rapidly signs and syndromes, and there was significantly difference between the two groups(P0.05). The complication incidence rate, hospitalization period and hospital charges in the treatment group were lower than those in the control group(P0.05). The amylase level, operation rate and mortality rate of the treatment group were also lower as compared with those of the control group, and there was no statistic difference(P0.05). ［Conclusion］ Treating SAP with RPRD in early stage may improve signs and syndromes, reduce the complication incidence rate, shorten the hospitalization period, and decrease the total hospital charges. 　　Key words：severe acute pancreatitis (SAP)；red peony root decoction (RPRD)；integrated traditional Chinese with western medicine ??? 重症急性胰腺炎（severe acute pancreatitis，SAP）是临床常见的急腹症，其起病急、病情凶险、并发症多、病死率高、疗程长、费用高。随着发病机制研究的进展、影像学的进步、重症监护的加强、手术时机及手术方式的改善、中西医结合治疗的开展，重症急性胰腺炎的病死率明显下降。我们重用赤芍治疗早期重症急性胰腺炎28例，疗效满意