新城疫疫苗对近年流行毒株的保护作用.pdfVIP

  • 26
  • 0
  • 约2.02万字
  • 约 4页
  • 2017-08-27 发布于湖北
  • 举报

新城疫疫苗对近年流行毒株的保护作用.pdf

新城疫疫苗对近年流行毒株的保护作用.pdf

AnimalHusbandryandFeeclScience。2OO9。1(3):32—35 Responsibleeditor.ZhangMingming Responsibletranslator.ZhangMingming Protective Efficacy ofNewcastle Disease Vaccines againstPrevalentStrainsinRecentY‘ears LIN Jian’。LIU Yue-huan’’。HAN Chun·hua’,MA Ming ,LIU Yong-hong。。PANJie’ 1.InstituteofAnimalHusbandryandVeterinaryMedicine,BeijingAcademyofAgricultureandForestrySciences,Beijing100097,China;2.Col- legeofVeterinaryMedicine,ChinaAgriculturalUniversity,Beijing100094,China;3.CollegeofAnimalScienceandVeterinaryMde icine,Inner MongoliaAgriculturalUniversiyt,Hohhot010018,China Abet阳ct O『bjective]ToinvestigatetheprotectiveefficacyofcurrentlyavailableNewacstlediseasevaccinesagainstcurrentlyprevalentstrains andthusprovideguidancefortheappliactionofvaccines andthepreventionandcomroIofNewacstledisease.IMethodlThe6一week-oldSPF chickenswererespectivelyinoculatedwithfiveIiveattenuatedNewacstlediseasevaccines(A.B。C.D.andE)atthedoes of1-foldor0.01-fold usageviaintranasaI.intraocularororalroute. er14dpostimmunization。thetiters ofHIantibodyworedetectde .AndalIthechickensworechal· lengedbyNewcastlediesaes virus(NDV)F E standardstrainortheisolatedwildstrains,NDV-2007-HBandNDV砌 8-YB.ThecliniacIsymp- tomsofchickenswerecontinuouslyobservde .andthemorbidiytandmortalityweredeterminde . R『esult]A什er14dpostimmunization.antibodies wereinducde ataprotectiveIeveIinchickensimmunizedwiththefivevaccines.AsshownbytheanimaIexperiment.thefivevaccinesatthedose 0f1-foldor0.01-foldusageprotectedalIvaccinatedchickensf帕m thedeathacusde byNDV 。Eastrain。andmorethan90% ofvaccinatedchick- ensfrom thedeathac ues dbyNDV-2007-HBstrain.whilethevaccines.A.B.andC.at thedoseof0.01-foIdusageprotectde morethan90% 0f vaccinatde chickensfr0mthedeathacuesdbyNDV硼 -YBstrain.fConclusion]Underlaboratoryconditions.thecurrentlyavailableNewcastle diseasevacc ineshavebetterprotectiveefficacyagainstthetwocurrentlyprevalentNDVstrainsandpreventtheoccurrence ofNewac stledisease. Keywerds Newac stledisease;

文档评论(0)

1亿VIP精品文档

相关文档