吸入普米克令舒佐治小儿毛细支气管炎疗效观察_临床医学论文.docVIP

吸入普米克令舒佐治小儿毛细支气管炎疗效观察_临床医学论文 吸入普米克令舒佐治小儿毛细支气管炎疗效观察_临床医学论文 【关键词】 普米克令舒佐 　　摘要：目的：探讨普米克令舒雾化吸入佐治小儿毛细支气管炎（毛支）的疗效。方法：将54例毛支患儿随机分为两组，两组均采用综合治疗，观察组加用普米克令舒雾化吸入，对治疗前后症状、体征持续时间、气道阻力参数进行比较。结果：观察组在治愈率、缓解喘憋、缩短哮鸣音及咳嗽持续时间、改善肺功能、降低气道阻力的作用均明显优于对照组（P＜0.05）。结论：普米克令舒雾化吸入治疗小儿毛支，可缩短病程，改善肺功能，疗效确切，且方便、安全，可作为佐治毛支的主要药物。 　　关键词:毛细支气管炎;普米克令舒;吸入 　　Study on the Clinical Effects of the Inhalation of Pulmicort　Respules on Bronchiolitis in Children 　　Abstract： Objective： To investigate the clinical effects of pulmicort respules(budsonide nebulising suspension)in halation on children with bronchiolitis.Methods： 54 cases,aged 36 days to 18 months,admitted to hospital with bronchiolitis,were divided into two groups randomly.27 cases in control group were treated with synthetic therapy and 27 cases in the other group were assist-treated with pulmicort respules inhalation based on the same synthetic therapy.The clinical effect,pulmonary function were evaluated in both groups.Results： The group with inhaled pulmicort respules showed a rapid improvement in respiratory symptoms(such as wheezing,cough and airway obstruction).The pulmonary functions also improved obviously in the pulmicort respules group compared with those in control group.Conclusion： The clinical symptoms of bronchiolitis can be controlled and the pulmonary function can be improved with the use of pulmicort respules inhalation,which is convenient and without many side-effects.It can be one of the principal drugs in the assist treatment of children with bronchiolitis. 　　Key words：Bronchiolitis；Pulmicort respules；Inhalation 　　毛细支气管炎（毛支）常见于2岁以内的小儿，多由呼吸道合胞病毒感染引起，亦有由人类3型副流感病毒、腺病毒感染引起毛支的报道［1］。其主要表现突起喘憋、有明显的毛细支气管阻塞现象，是儿科常见急症，至今尚无特效的治疗。本文用普米克令舒（pulmicort repules,布地奈德混悬液）雾化吸入佐治27例毛支患儿，报道如下。 　　1 资料与方法 　　1.1 临床资料：研究对象为2003年12至2004年5月我科收治确诊的54例毛支患儿，全部病例均无呼吸衰竭、心力衰竭等并发症，并除外先天性心脏病、结核感染及支气管异物等疾病。全部病例均符合有关毛支的诊断标准［2］，并随机分为两组。观察组27例，男15例，女12例；对照组27例，男13例，女14例。两组年龄为36天至18个月。入院时均有阵发性咳嗽、喘憋、气促，心率快，肺部有哮鸣音及小水泡音。两组间病例数、性别、年龄、病程均无显著性差异（P＞0.05）。 　　1.2 方法：两组患儿均采用相同的综合