养阴清热法对2型糖尿病胰岛素抵抗影响_张毅.pdfVIP

辽宁中医杂志 2010年第 7卷第 4期 # 689# 2 , , (上海市中医医院内分泌科, 上海 200071) : 目的:观察养阴清热法中药对 2型糖尿病胰岛素抵抗的影响方法: 将 80例 2型糖尿病胰岛素抵抗患者随 机分 治疗组 40例和对照组 40例两组患者均经饮食调控停用降脂药, 两组均用磺脲类和双胍类降糖药物, 经过 2 周的平台期观察后, 治疗组在此基础上加用养阴清热法中药治疗, 疗程 8周治疗前后观察: 空腹胰岛素 ( FIns), 空腹血 糖( FPG), 餐后 2h血糖( 2hPG) , 糖化血红蛋白( H bA 1C)等指标的观察, 并计算胰岛素抵抗指数( HOMA - IR)结果: 治 疗组总有效率优于对照组(P 01 05), 降低血糖血脂空腹胰岛素, 改善胰岛素敏感性方面, 差异具有显著性意义(P 01 05 或P 0101) 结论: 中药在降糖降脂的同时能显著改善患者的胰岛素抵抗 : 2型糖尿病; 胰岛素抵抗; 中医药疗法; 养阴清热 : R58711 : B : 1000- 1719(2010) 04- 0689- 0 Influence on Insutin Resistance of Type 2 DiabetesM ellitus by the Treatm ent ofYangyin Qingre ZHANG Yi, TANG H ong, ZHAN G M in (E ndocrine D ep atm ent of ShanghaiH osp ital of TCM, Shanghai 200071, China Abstract: Obj ective: To observe the law Yangyin Q ingre Ch inesem edicine for type 2 diabetes the effects of insulin res istance. M ethods: 80 cases of insu lin resistance in type 2 diabetic patientsw ere random ly d ivided into treatm ent group 40 cases and 40 ca- ses of the control group. Tw o groups of patients by d iet contro,l lipid-low ering drugs to disable the wt o groupsw ere used su lfony- lurea and M etform in Hypoglycem ic drug, after a period of wt o w eeks of the observation platform, the treatm ent group on the basis of additional treatment w ith Ch inesem edicineQ ingre Yangyin, treatm ent for 8w eeks. Observed before and after treatm ent: fasting insu lin, BM I, FPG, 2hPG, H bA 1C, and other ind icators of the observations, and calculate the insu lin resistance index( HOMA - IR) .R esults: The results of the efficiency of the treatm ent group therew ill awl ays be better than the control group(P 01 05 orP 01 01), low er b lood glucose,