谷氨酰胺和烧伤免疫营养.pdfVIP

·专家论坛· 谷氨酰胺与烧伤免疫营养 彭曦 汪仕良 and burn PENG Glutamineimmunonutritionfor patients 能，维护内环境稳定，改善患者 Bum ltos— xi，WANG of Research．Southwest Shi—liang．Institute 预后的目的。 and In一 Combined pital，StateKeyLaboratoryofTrauma。Burns 免疫营养(immunonutri． Third Medical 皿ry。the Military University，Chongqing400038， China tion)是营养支持发展到营养治疗的具体体现，其核 Nutritionalisan determi- 【Abstract】 therapyimportant 心是在普通营养配方基础上添加一些具有特殊功能 nantofimmunefunctioninburn patients．However，common 的营养素，利用其药理作用对疾病进行主动干预，在 nutritional tO withextensivebum supplementgivenpatients deep isstill inefficienttoblocknutrientsutilizationdue 细胞、分子水平调节机体应激、代谢、炎性反应和免 therapeutically tOmetabolicdisorder．Immunonutrition．anewnutritionthera- 疫状况。已用于烧伤临床的免疫营养素有谷氨酰胺 peutic beenusedin burned for modality．has severely patients cell metabolic enhan· regulatingfunction，improvingstate，and 维生素、微量元素以及益生菌等睢】。本文中，笔者 immune oftenconsideredtO cing function．Glutamine(Gin)is 重点介绍Gin，探讨其作用机制、应用现状和存在的 bea immunonutrientinimmunonutritionforcriti- prime therapy ill thosewithseriousbums．Ourseries 问题。 tallypatientsincluding of andclinicalstudieshavedemonstratedthatGln experimental administeredin or abate animals could intestinal patients iniury， 1 Gin与烧伤免疫紊乱 accelerateofintestinal repair mucosa，improvenitrogenbalance， abate maintainimmune