人参皂苷Rb1对大鼠成骨细胞增殖_分化和OPG_RANKLmRNA表达的影响.pdfVIP

( ) • 939 • 中华中医药杂志 原中国医药学报 2010年6 月第25 卷第 6 期 CJTCMP , June 2010, Vol . 25, No.6 ·研究报告· Rb1OPG/ RANKL mRNA 王俊俊，江洋珍，梁继超，陈勇 摘要： κ P P P P P 关键词： Effects of ginsenoside Rb1 on cell proliferation,differentiation and OPG/RANKL mRNA expression of rat osteoblast cultured in vitro WANG Jun-jun,JIANG Yang-zhen,LIANG Ji-chao,CHEN Yong (Key Laboratory of Biotechnology of Chinese Medicine,Hubei University,Wuhan 430062,China) Abstract: Objective: To study the effects of ginsenoside Rb1 on cell proliferation,differentiation and OPG/RANKL mRNA expression of rat osteoblast cultured in vitro.Methods:Rat osteoblast cultured in vitro was treated by a series of different concentration of ginsenoside Rb1 for different time respectively.The proliferation of osteoblast was detected by MTT method.The differentiation of osteoblast was detected by the activity of ALP.mRNA expression of osteoproteger