体外无线供能的植入式单穴位电针系统的研究.pdfVIP

体外无线供能的植入式单穴位电针系统研究 Study of implantable uni-acupoint electroacupuncture system 1 刘枭寅 郝红伟牛川森 李路明 卢峻 图娅 （清华大学航天航空学院，北京 100084 北京中医药大学，北京 100029 ） Liu Xiaoyin, HaoHongwei, Niu Chuansen, Li Luming; Lu Jun, Tu Ya (School of Aerospace, Tsinghua University, Beijing 100084 Beijing University of Chinese Medicine, Beijing 100029) 摘要： 目前国内外的电针系统通常为有线连接方式，用导线连接刺激仪与一对电极，分别刺激两个穴位形成通路。不仅治疗和实 验中有所不便，而且不利于穴位特异性的研究。为此，我们开发了一种植入式单穴位电针系统，分为体外控制器和体内刺 激器两部分，体内刺激器植于皮下穴位处，体外控制器通过电磁耦合将控制信号及刺激能量发送到体内刺激器上，实现对 单个穴位的电刺激的无线控制方法。为保证植入安全，应用了生物相容性涂层。将此系统应用于家兔镇痛实验中，通过对 照实验行为疼痛评分显示电针系统对家兔有显著的镇痛效果，组织学切片观察结果显示生物可靠性良好。 关键词：神经科学 电针 电磁耦合 疼痛评分 Abstract: Recent electroacupuncture systems are mainly wired and bi-acupoint which forms a current loop, as causes many inconveniences for clinical use and acupoint specification study. To overcome these problems we developed a wireless uni-acupoint implantable electroacupuncture system, consisting of an external controller and an implanted stimulator which can be implanted into acupoint and only needs very small circuit to receive RF power from the controller. Additionally we adopted some biocompatible material in manufacture to ensure bio-safety. Finally we designed an analgesia experiment on rabbits, results of which show that electroacupuncture has obvious antinociceptive effects for rabbits, and this system has good biocompatibility. Keywords: neuroscience electroacupuncture electromagnetic coupling pain score 1 背景及介绍 [1][2][3] 针灸治疗在中国以及其他一些东方国家有长达 3000 年的历史，近些年来