参附注射液配伍对乌头碱诱发心律失常的减毒研究_肖勇.pdfVIP

12 中药药理与临床20 13 ;29 (3) 16 ， ． ． ，2008 ;10 (4 )∶ 3 ～ 5 门振华 王庆西 天门冬氨酸转氨酶同功酶在肝脏疾病中检测的意 肝病中的作用 西南军医 ． ，2004 ;15 (2)∶ 65 ～ 66 18 ， ． ． 义 齐鲁医学检验 孙丽霞 周玲玲 柴胡疏肝散对大鼠免疫性肝损伤的防治作用 中 17 ， ． 、 ，20 12 ;33 (5)∶ 629 ～ 630 刘翼 李昌平 氧应激 脂质过氧化及肝细胞凋亡在非酒精性脂肪 国生化药物杂志 Influence of chaihushugan powder on lipid metabolism and liver function in nonalcoholic fatty liver rats Li Dan1 ，Jiang Tao2 ，Fan Huaqian1 ，Liang Wannian1 ，Xiong Kechao1 ，Tang Chunping1 1 (School of Chinese Material Medica of Guangdong Pharmaceutical University ; 2 Laboratory Animal Center of Guangdong Pharmaceutical University ，Guangzhou 510006) Objective :To investigate the effects of Chaihushugan powder on lipid-lowing and liver-protecting of nonalcoholic fatty liver disease (NAFLD)rats． Methods :The rats were randomly divided into normal control group ，model group ，Dongbaogantai group (0 ． 09g methionine / kg)，Chaihushugan powder high ，medium ，low doses (12 ． 6 ，6． 3 ，3． 15g / kg)． In addition to the normal group ，the other group was adminis- tered by i． g high fat and sugar emulsion in the morning ，four hours later ，each group was interfered corresponding medicine ，the control group and model group were given normal saline． The rats were fed for 8weeks． At the end of the experiment ，detected blood lipid ，FFA ，liver function ，liver total cholesterol ，TG ，MDA ，SOD ，T-GSH in each group rats ，calculated the liver index ，observed the liver pathological chan- ges