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II
Effect of Nour i sh i ng Q i to Stop Co I i apse on Hemodynam i cs of
Hypodynam i c Shock by Us i ng the Pu I se I nd i cator Cent i nuous
Card i ac Output Men i tor
SpeciaI ity:01 inical intergrated chinese
and western mediciRe
Author:
Tutor:
Abstract
Object Ive
The purpose of thi s study was to observe
the effect of shengmai injection
which is composed on the basis of nourishing qi to stop collapse
in hypodynamic
shock Datients.Comparing the changes of brain natriuretic peptide(BNP)、
shock index(SI)and the hemodynamic parameter through pulse indicates
continuous cardiac output(PiCCO)monitor,further discuss its mechanism·
Methods
24 hypodynamic shock patients were randomized
into 2 groups:the comparlon
group(12 patients)and the experiment group(12 patients),both of which were
given fluid resuscitation and vasoactive agent.The 5%glucose injection 310ml
was dripped intravenous infusion in the comparion group,while shengmai
in jection 60ml was dripped with 5%glucose injection 250ml in the experiment
group.For venOUS blood collection at the same time,test BNP and
SI of two groups·
After 8 hours.observed the changes of patients’cardiac index(CI)、global end
diastolic volume(GEDI)
extravascular lung water
、systemic vascular resistance index(SVRI)、
(EVLW)、mean artery pressure(MAP)、SI and BNP.
ReSUltS
BNP was decl ined in both groups,while of which only the experiment group
went down significantly(PO.05).The CI、GEDI、MAP of both groups rose up to
the normal level.It was noticed that the increase detected in the experiment
group was higher(P0.05).SVRl was decl ined in both groups,while of which
only the experiment group went down to the
normal level(P0.05).No obvious
change of EVLW was detected between
ei ther group(P0.05).
ConeIUSions
As the main prescription for nourishing qi to stop collapse,shengmai
in jection has a beneficial effect on hypodynamic shock by increasing cardiac
III
output and reduction in peripheral
Hemodynamics.
Key Words:nourishing qi to stop
hypodynam
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