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MTBI Scientific Update: Lessons Learned from Sports Concussion Research Michael McCrea, PhD, ABPP-CN Mild Traumatic Brain Injury and Postconcussion Syndrome:The New Evidence Base for Diagnosis and TreatmentMichael McCrea, PhD, ABPP-CNNeuroscience Center, Waukesha Memorial HospitalDepartment of Neurology, Medical College of Wisconsin Objective: MTBI from A to Z Review and gain a clearer understanding of: MTBI on the all-Severity TBI Landscape Basic and Clinical Science of MTBI The True Natural History of MTBI Implications for Rethinking Postconcussion Syndrome Unpaid Political Announcement MTBI, more than any other clinical entity, is a neuropsychological construct The contribution by neuropsychologists to MTBI research is unmatched by any other discipline Neuropsychologists are uniquely suited to evaluate and treat MTBI Neuropsychologists should not limit their role in MTBI just to neuropsych testing Concussion Research Consortium (CRC) Part 1: The TBI Landscape Epidemiology and impact of all-severity TBI Zeroing in on MTBI: Epi and Impact Challenges in Defining Diagnosing MTBI Advances in MTBI research methodologies Top 10 Conclusions Traumatic Brain Injury: The Big Picture Major public health problem world wide 1.4-3.0 million cases/yr in US Leading cause of death disability: 50-100K TBI deaths/yr in U.S. 40+% of all trauma fatalities in US each year At risk: very young/very old, males, minorities, low SES, substance abusers Cost: ~ $100 billion/yr in US The Forgotten Entity Significance of MTBI: “Silent Epidemic” Challenges in Defining Diagnosing MTBI Classifying TBI severity an imperfect science Varied emphasis on acute injury characteristics Limitations of traditional methods (GCS) Limited reliability, validity, predictive power of newer classification methods Numerous case and administrative definitions MTBI Definitions The Elusive MTBI Denominator: Research Implications The Elusive MTBI Denominator: Clinical Implications Injury Severi