Dragon#39;s Blood Capsules Loureirin B Determination and comparison of.docVIP

 PAGE \* MERGEFORMAT 11 Dragon#39;s Blood Capsules Loureirin B Determination and comparison of Keywords: Dragon’s Blood Capsule;,, Loureirin B;,, high-performance liquid chromatography Abstract: Objective Determination of HPLC Dragon Dragon’s Blood Capsules Blood-B levels, simplifying pre-treatment, and different brands marketed in the Long Dragon’s Blood Capsules Blood-B levels were compared. Methods column Eclipse XDB-C18 (5 μm, 4.6 mm × 150 mm, Agilent), acetonitrile 0.4% phosphoric acid (35:65) as mobile phase, flow rate of 1 ml / min, column temperature 30 ℃, The detection wavelength was 275 nm. Dracaena-B results in 6.2 ~ 31.5 μg / ml and the peak area within the linear relationship was good (r = 0.999 99, n = 5), Long-B increases the blood sample recovery 99.66% (RSD = 1.48%). Conclusion The method is simple, accurate, reliable, easy preparation of the content of the daily production control, and marketed in different brands of Dragon’s Blood Capsules Dracaena-B levels are in line with national standards (not less than 0.6 mg / tablets). Keywords: Dragon’s Blood Capsule; Loureirin B; high performance liquid chromatography Abstract: ObjectiveTo establish an HPLC method for determination of Loureirin B in dragon blood capsules, and make a comparison of loureirin B in dragon blood capsules of different brands.MethodsThe chromatographic column of Eclipse XDB-C18 was used. The mobile phase was composed of acetonitrile -0.4% phosphoric acid (35:64) and the flow rate was 1 ml / min. The detection wavelength was 275 nm.ResultsThe standard curve of Loureirin B was linear in the concentration range of 6.2 ~ 31.5 μg / ml, r = 0.999 99. The average recovery was 99.66%, RSD 1.48%. ConclusionThe method was simple and reliable for determination of Loureirin B. The content of Loureirin B in dragon blood capsules of different brands all matched a national standard. Keywords:: Dragon’s blood capsules; Loureirin B; HPLC “Dragon’s B