Experimental Research of magnesium alloys in vivo degradation and bone reaction of the animal experiments to explore.docVIP

 PAGE \* MERGEFORMAT 13 Experimental Research of magnesium alloys in vivo degradation and bone reaction of the animal experiments to explore Of: the country rather, smell for a long time the whole, Pan Feng, Jiang read, Zhang Erlin, XU Li-ping, Fan Guangyu [Abstract] [Objective] animals implanted magnesium alloy femoral shaft after the degradation process in magnesium alloy, metal - bone interface of the bone response mechanisms. [Method] in the SD rats in the lateral femoral implant alloy metal rods, after anti-inflammatory, free, 9 weeks later specimens were observed under the microscope metal - bone interface changes in the macro, scanning electron microscopy (SEM observed metal - the microscopic changes in bone interface, the application spectrum analysis (EDS) techniques to determine elemental composition, and will stick to do decalcified bone section staining, light microscopy of metal - bone histological changes. [Results] With the femur in the degradation of magnesium alloy, magnesium alloy surface and the surrounding bone degradation bone surface reactions occur simultaneously in the metal - bone formation in close proximity of the metal layer, degradation level, the new bone layer 3 level, students no inflammatory cell infiltration of bone surface, showing a small amount of discontinuous fibrous connective tissue. [ Conclusion] The metal - bone interface of the bone response to fully comply with the normal bone healing process, new bone and normal bone structure of exactly the same form, it can infer that the degradation of magnesium alloy with good resistance, bone and tissue compatibility , the degradation process and the process of new bone into the bone with good synchronization. [Keywords:] magnesium alloy, the degradation of bone response Abstract: [Objective] To study the mechanism of magnesium alloy degradation and bone formation at the bone implant interface after implanting a magnesium alloy into rat femur. [Method] SD rats femur