Experimental spleen deficiency rats serum enzyme analysis of 10.docVIP

 PAGE \* MERGEFORMAT 11 Experimental spleen deficiency rats serum enzyme analysis of 10 Of: YIN Wei-dong Xiao Wen Jing Wen Xiaoyan Liu Keqin [Abstract] Objective: To investigate the spleen lead to the pathophysiology of edema. Methods: The method Laojuan shape and irregular diet deficiency model in rats to compare the serum AST, ALT, ALP, CHE, 5 NT, LDH, LDH1, @ HBD , CK, CK MB10 kinds of activity and the differences between the control group. Results: The spleen group LDH, LDH1, ALP, 5 NT compared with control group decreased significantly (P lt;0.01, AST, CK MB, @ HBD, CK was significantly lower (P lt;0.05, CHE was significantly higher (P lt;0.05, ALT reduced but no significant difference (Pgt; 0.05. Conclusion: The deficiency caused by a variety of serum enzyme changes, reflecting the pathological liver and heart damage, impaired function of the two organs may lead to deficiency causes edema. [Keywords:] rats, spleen, serum, enzyme [ABSTRACT] Objective: To study the pathophysiologyical mechanism from syndrome of spleen deficiency to dropsy.Methods: The rat model with syndrome of spleen deficiency was made by the way of tiring and disordered feast and hunger, and the difference was compared between syndrome of spleen deficiency group and normal group for the levels of 10 serum enzymes, AST, ALT, ALP, CHE, 5 NT, LDH, LDH1, @ HBD, CK, CK MB.Results: The leves of serum enzymes for LDH, LDH1, ALP , 5 NT in the rats with syndrome of spleen deficiency were much notablely lowwer than that of normal group (P lt;0.01, the AST, CK MB, @ HBD, CK were notablely lowwer (P lt;0.05, but the CHE was notablely higher than that of normal group (P lt;0.05.Conclusion: The changes of more enzymes in rat serum were processed by syndrome of spleen deficiency, indicating pathological damages for liver and heart, and the functional damage was the reason which syndrome of spleen deficiency would be dropsy. [KEY WORDS] Rat, Spleen Deficiency, Serum, Enzyme At pres