Experimental study of anti-influenza virus medicine Progress.docVIP

 PAGE \* MERGEFORMAT 5 Experimental study of anti-influenza virus medicine Progress [Keywords:] Experimental Study of traditional Chinese medicine of anti-influenza virus Influenza viruses are sticky Branch virus, is a kind of sticky protein, has a special affinity for RNA viruses. According to the different parts of the virus antigen is located within the antigen and the outer antigens are divided into two categories: the core of the internal antigens single-stranded RNA protein; outer glycoprotein antigens, including hemagglutinin (Hemagglutinin, H) and neuraminidase ( Neuramindase, N). According to the different nature of its antigen, influenza viruses are divided into A (A), B (B), C (C) type; in turn divided into a number of its virus subtypes (H1 ~ H15, N1 ~ N9). B-and C-type influenza virus antigen more stable, A-type is the major pathogens causing epidemic and its virus surface antigens HA and NA more easily mutate. At present, prevention and treatment of influenza M2 ion channel mainly western inhibitors, NA inhibitors and influenza vaccines, the former two drugs side effects of relatively large, and with the wide range of applications, easy to produce drug-resistant, while the only known influenza vaccine virus subtypes have a preventive effect, for by antigenic drift or antigenic conversions generated by new influenza viruses. Therefore, the anti-influenza virus drug research is particularly important and urgent. Influenza in Traditional Chinese Medicine called ‘when the line of a cold’, is a pestilence class (ie communicable diseases), Chinese medicine that the human feelings of Feng Xie (pathogens) attack, while the body’s immunity is low, not enough anti-evil and disease, particularly As abrupt climate change, more disease when the cold warm disorders. TCM fundamental role of anti-influenza virus rousing or Quxie righting mechanism. Although each component more complex taste of Chinese medicine, Chinese medicine prescription mechanism of action