Four kinds of licorice in human breast cancer cell proliferation and induce apoptosis Comparative Study.docVIP

 PAGE \* MERGEFORMAT 11 Four kinds of licorice in human breast cancer cell proliferation and induce apoptosis Comparative Study 【Abstract】 Objective To compare the active ingredient in Xinjiang four kinds of wild licorice on human breast cancer cell proliferation with a view to filter out the pharmacodynamics of the best types of licorice. Methods MTT assay in different samples of the BCAP  37 cell proliferation, Hoechst33258 fluorescence staining of the samples BCAP  37 cells induced apoptosis. The results of four kinds of active ingredients of licorice in human breast cancer BCAP  37 cells, has significant growth inhibition and induction of apoptosis, and there are significant differences between species and origin. Conclusion The best anti-cancer efficacy of Alar licorice licorice species. Keywords: Glycyrrhiza active ingredient of human breast cancer cells, BCAP 37 Comparative Study on the Anti-proliferation and Apoptosis-inducing Effects of Active Components from Four Glycyrrhiza Species on Human Breast Cancer BCAP-37 Cell Abstract: ObjectiveTo select the optimal glycyrrhiza species for medicinal utilization by comparing the anti-proliferation and apoptosis-inducing effects of active components from four wild glycyrrhiza species in Xinjiang on human breast cancer BCAP  37 cell. MethodsThe anti-proliferation effects of different samples on BCAP  37 cell were measured by MTT assay. The cell apoptotic rate was detected by Hoechst 33258 stain.ResultsActive components of four Glycyrrhiza species inhibited the proliferation of BCAP  37 cells and induced apoptosis significantly. What’s more, there were significant interspecific and spatial variations in the anti-proliferation and apoptosis-inducing effects. ConclusionThe optimal Glycyrrhiza species for anticancer utilization is Glycyrrhiza alalensis L. Keywords:: Glycyrrhiza; Active Component; Human breast cancer BCAP  37 Cell Licorice is a very important trad