HPLC determination of sodium bicarbonate tablets of rhubarb and rhubarb phenol content of emodin.docVIP

 PAGE \* MERGEFORMAT 9 HPLC determination of sodium bicarbonate tablets of rhubarb and rhubarb phenol content of emodin [Abstract] [aim] Rhubarb by high performance liquid chromatography and sodium bicarbonate tablets Chrysophanol emodin content. [Method] HPLC; column was Shim pack clc ODS (150 6.0mm, 5.0um, mobile phase of methanol 0.1% phosphoric acid (85:15, flow rate 1.0ml/min, detection wavelength 254nm. [Results] The linear relationship was good. emodin and chrysophanol average recoveries were 98.5% , 99.3%, RSD = 1.3%, 0.4% (n = 9. [Conclusion] The method is simple, accurate, and reproducibility, and can be used for quality control of rhubarb sodium bicarbonate tablets. [Key Words] high performance liquid chromatography; rhubarb sodium bicarbonate tablets; emodin; Chrysophanol Abstract: [Objective] TO establish an HPLC method for the determination of emodin and chrysophanol in rhubarb sodium bicarbonate tablets. [Methods] An HPLC method was applied; Chromatographic column was Shim pack clc ODS (150 6.0mm, 5.0um; The mobile phase was methanol 0.1% phosphoric acid (85:15; Velocity of flow was 1.0ml/min; The detaction wavelength was 254nm. [Resulet] The linearty of this method was well.Emodin and chrysophanol average recovery rates were 98.5%, 99.3% ; RSD = 2.75%, 2.83% (n = 9. [Conclusion] This method is simple, accurate with strong reproducibility, and can be used for the quality control of rhubarb sodium bicarbonate tablets. Keywords:: HPLC; rhubarb sodium bicarbonate table; emodin; chrysophanol Rhubarb is a compound of sodium bicarbonate tablets, the main ingredient is rhubarb, sodium bicarbonate, peppermint oil etc., is Zhuxiaohuayao and antacid drugs category of non-prescription drugs, mainly for lack of appetite, excessive stomach acid [1]. Rhubarb sodium bicarbonate on Quality Standards made by the Ministry of Health standards for chemical and pharmaceutical preparations in the first volume [1], did not determine the content of th