Huaier extract on human hepatocellular carcinoma cell lines Inhibition of metastasis.docVIP

 PAGE \* MERGEFORMAT 12 Huaier extract on human hepatocellular carcinoma cell lines Inhibition of metastasis Author: Li Lixin YE Sheng Wang Yanhong XUE Qiong Jie Gao Dongmei Tang ZY Rui-Xia Sun Abstract [Objective] To explore Huaier extracts inhibited liver cancer cell transfer mechanism for Trametes robiniophila in clinical treatment of liver tumors provide a theoretical basis. [Methods] the high-metastatic potential of human hepatocellular carcinoma cell line (MHCC97H) respectively Huaier extract (1.0mg/ml, 3.0mg/ml, 5.0mg/ml, 10.0mg/ml) and DMEM (containing 10% fetal bovine serum) the role of 24h, measured by the rate of tumor cell adhesion, movement and invasion inhibitory rate of inhibition. [Results] cells in each group by Trametes robiniophila MHCC97H the role of 24h, the cell adhesion rate decreased significantly, while the inhibition rate of movement and invasion inhibition was significantly increased compared with the control group were statistically significant differences, and the Baptist Huaier Cream concentration and the rate of tumor cell adhesion, movement inhibition rate and inhibition rate of invasion are relevant. [Conclusion] Sophora japonica extract significantly inhibited the ear hepatoma cell adhesion, movement and invasion, it could inhibit the transfer of hepatocellular carcinoma cells. Keywords: hepatocellular carcinoma cell line Trametes robiniophila metastasis suppressor Metastatic Potential Inhibited with Trametes Robiniophila in Highly Metastatic PotentialHuman Hepatocellular Carcinoma Cells Lines Abstract: [Purpose] To explore the mechanism of metastatic potential inhibited with Trametes robiniophila in human hepatocellular carcinoma cells andto provide the experimental basis of Trametes robiniophilain treatment for liver cancer. [Method] Highly metastatic potential human hepatocellular carcinoma cells (MHCC97H) were treated with DMEM and Trametes robiniophila (1mg/ml, 3mg/ml, 5mg/ml and 10mg/ml) f