Hydroxyl radical degradation of seaweed sulfated polysaccharides of the feasibility study.docVIP

 PAGE \* MERGEFORMAT 13 Hydroxyl radical degradation of seaweed sulfated polysaccharides of the feasibility study Author: Yue true, Lishou Ling, Li Xi, Qu Aegean [Abstract] Low molecular weight sulfated polysaccharides from brown seaweed has been proved to be a variety of biological functions, but the seaweed sulfated polysaccharides extracted large molecular weight, the need for further degradation. Some degradation of the most commonly used methods have some shortcomings, need to find new ways of degradation. Hydroxyl radicals as a highly active substance of biological macromolecules are highly damaging. According to this nature of the inference can be a degradation of polysaccharide hydroxyl radicals a powerful tool. Paper summarizes the international and domestic progress in the use of free radical degradation of polysaccharides to study the mechanism of free radical degradation of polysaccharides, and degradation of seaweed sulfated polysaccharides radical prospect. [Keywords:] hydroxyl radical degradation of seaweed sulfated polysaccharides Seaweed sulfated polysaccharides Laminaria polysaccharide sulfate, is present in the alginate polysaccharide in plant cell material, the main component is α -L-fucose 4 - sulfuric acid ester polymer, and also contain different proportions of galactose, mannose, xylose and glucuronic acid, has been shown capable of regulating immune activity, anti-tumor, anti-radiation, lowering blood pressure, lowering blood sugar, anti-thrombosis, anti-oxidation and other biological functions, is a potential source of marine drugs, but the seaweed sulfated polysaccharides medicinal road still exist many problems. Extracted from kelp seaweed sulfated polysaccharide and its molecular weight was mostly in the hundreds of thousands or even millions, molecular weight greater immunogenicity strong, to the physical and chemical properties and biological function analysis of the difficulties stemming from the research, but also highly