Hyperbaric oxygen combined with edaravone Clinical observation of traumatic brain injury.docVIP
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Hyperbaric oxygen combined with edaravone Clinical observation of traumatic brain injury
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Hyperbaric oxygen combined with edaravone Clinical observation of traumatic brain injury
[Abstract] Objective To observe the hyperbaric oxygen combined with edaravone clinical traumatic brain injury. Methods 80 cases of brain injury patients to hyperbaric oxygen combined with edaravone at the same time be appropriate symptomatic treatment. The result of hyperbaric oxygen combined in accordance with edaravone treatment of traumatic brain injury, the total effective rate was 97.5%, no obvious side effects of drugs. Conclusion edaravone hyperbaric oxygen combined with safe and effective treatment of brain injury, it is worth further clinical application.
[Key Words] high-pressure oxygen; edaravone; brain injury; combination therapy
Traumatic brain injury is a common one, accounting for the total number of trauma 1 / 5, but the disability is living in the first place [1], in clinical practice has a significant place on, has also been the focus of clinical research and hot topics .2006 In March ~ February 2010 in 80 cases during the hospital traumatic brain injury to hyperbaric oxygen combined with edaravone, a significant effect, are as follows.
1 Clinical data
1.1 Object Selection
Inclusion criteria: (1) age 18 to 65 years; (2) a clear history of head injury, Glasgow score (GCS) score of 4 to 8 pm; (3) traumatic brain injury within 6h; (4) No chest , abdominal organs, and complex skull fractures and other serious injuries; (5) before treatment, do not use drugs or other similar edaravone metabolism and pharmacological effects of drugs may have an impact; (6) no serious systemic disease.
Exclusion criteria (1) age lt;18 orgt; 65 years; (2) previous history of serious chronic diseases such as hypertension, coronary heart disease, diabetes, liver and kidney dysfunction, etc.; ALT, Cr 2 times the upper limit of normal than those who ; (3) brain organic diseases such as brain tumor; (4) pregnant or lactating women; (5), aller
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