Hyperbaric oxygen therapy on patients with severe traumatic brain injury in serum C-reactive protein.docVIP
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Hyperbaric oxygen therapy on patients with severe traumatic brain injury in serum C-reactive protein
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Hyperbaric oxygen therapy on patients with severe traumatic brain injury in serum C-reactive protein
Keywords: C-reactive protein
C-reactive protein (C-reactive Protein, CRP) is the body’s infection, trauma caused by tissue damage synthesized by the liver, an acute-phase protein. Normal serum CRP concentration is very low, when the body’s inflammation or tissue damage occurs, its concentration can be increased significantly within a few hours. CRP as a non-specific inflammatory response in vivo a sensitive marker for one of the commonly used anti-inflammatory and immunosuppressive drugs on CRP levels was not obvious. Now researchers are more concerned with its content changes and the relationship between traumatic brain injury to resume. Authors through the analysis, coupled with high-pressure oxygen chamber therapy and with conventional methods, treatment of severe traumatic brain injury patients, to observe the changes in serum CRP levels are reported as follows.
1 Data and methods
1.1 General Information
From June 2006 to December 2007, the Court 60 patients, male 41 cases, female 19 cases; aged 12 to 70 years. Have a clear history of trauma, of which 15 cases of injury fall height, car accident injuries 42 cases of heavy hit and wounded in 3 cases. The head CT scan diagnosis, no other organ injury. GCS score 3 to 5 minutes in 28 cases, 5 ~ 8 minutes 32 cases. 21 cases of intracranial hematoma, intracranial hematoma in 30 cases with brain contusion, diffuse axonal injury in 9 cases; surgical treatment of 47 cases, non-surgical treatment of 13 cases. Were randomly divided into hyperbaric oxygen therapy (HBO) group and control group, n = 30 cases, two sets of injury, age, GCS score differences were not significant.
1.2 Treatment
The control group of conventional surgery and postoperative dehydration, nutritional support and symptomatic treatment-related, HBO treatment group in the correspond
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