In advanced esophageal course accelerated radiotherapy plus concurrent chemotherapy in clinical studies.docVIP

 PAGE \* MERGEFORMAT 12 In advanced esophageal course accelerated radiotherapy plus concurrent chemotherapy in clinical studies [Keywords:] esophageal neoplasms / radiotherapy, esophageal cancer / chemotherapy, prognosis To investigate the course accelerated hyperfractionated radiotherapy plus concurrent chemotherapy and radiotherapy treatment of esophageal cancer efficacy and improve the local control rate, in order to improve the survival rate of esophageal cancer, this study of 96 patients with advanced esophageal cancer patients were divided after the course accelerated radiotherapy and chemotherapy and conventional radiotherapy alone, a prospective randomized controlled study. 1 Materials and methods 1.1 Case Selection The group of 96 patients, male 65 cases, 31 females, were pathologically or histologically proven squamous cell carcinoma, age lt;75 years, Karnofsky scoregt; 60 points, lesion length 10 cm, previously did not receive radiotherapy and chemotherapy and surgical treatment, no signs of active bleeding and perforation, liver and kidney function before treatment, blood was normal, semi-liquid diet can be hired, no serious medical illness, all enrolled patients before radiotherapy, abdominal CT and ultrasound B, not abdominal lymph node metastasis was found. envelopes were randomly divided into late-course accelerated hyperfractionated radiotherapy plus concurrent chemotherapy group (radiochemical group) and radiotherapy group (RT group). radiotherapy alone group 32 males and 16 females, median age of 58.6 years, mean lesion length (6.0 +-1.7cm, cervical in 3 cases, 8 cases of upper, middle in 32 cases, 5 cases of lower radiochemical group of 33 males and 15 females, median age 57.4 years, mean disease length (6.2 +-1.5cm, cervical in 5 cases, 10 cases of upper, middle in 29 cases, lower in 4 cases. two ages, the lesion and lesion length compared with no significant difference (Pgt; 0.05, comparable. 1.2 Treatment All patient