Infants with congenital heart disease with moderate to severe pulmonary hypertension in surgical treatment of.docVIP

 PAGE \* MERGEFORMAT 5 Infants with congenital heart disease with moderate to severe pulmonary hypertension in surgical treatment of [Keywords:] congenital heart disease; pulmonary hypertension; infants and young children; surgical treatment of Since August 1996 to December 2003 in our hospital 58 cases of congenital heart disease with moderate to severe pulmonary hypertension in infants and young children line correction surgery. Is now on the timing of surgery, surgery, and perioperative management of the main points reported as follows. 1 Materials and methods 1.1 Clinical data A total of 57 cases of this group of patients, 33 males and 24 females, aged 4.5-36 months, mean (17.6 ± 12.4) months, weighing 4.5-12.5kg, the average (8.9 ± 3.6) kg. Diseases, including ventricular septal defect (ventricular septal defect, VSD) 36 cases (including 4 cases with pulmonary valve stenosis, 6 cases of right ventricular outflow tract obstruction, 2 cases of tricuspid regurgitation), complete endocardial cushion defect in 3 cases, ventricular septal defect ASD (atrial septal defect, ASD) 14 cases, ventricular septal defect ASD patent ductus arteriosus (patent ductus arteriosus, PDA) 4 Li. Both rest and activity cyanosis, heart murmur is not a typical four cases, all patients breath sounds lungs are thicker, some can be heard and dry rales. Arterial partial pressure of oxygen (60.63 ± 9.68) mmHg, oxygen saturation (90.63 ± 7.69)%. Moderate pulmonary hypertension (Pp / Ps of 0.45-0.75) were 45 cases (78.9%), severe pulmonary hypertension (Pp / Ps ≥ 0.75) in 12 cases (21.1%), with an average of 0.69 ± 0.13. Pulmonary circulation flow and circulation of cases by conventional chest radiography, electrocardiogram, cardiac echocardiography and other tests, the diagnosis. 1.2 Perioperative 2-4 weeks before surgery to give oxygen and give captopril 1-2mg / (kg * d). With pulmonary infection, a positive use of antibiotics, infection control, to control heart failure, c