Injection on Myocardial Injury.docVIP

 PAGE \* MERGEFORMAT 9 Injection on Myocardial Injury [Abstract] Objective To observe Injection on isoproterenol induced myocardial ischemic injury. Methods isoproterenol rat model of myocardial ischemia, BL-420 Recorders Record rat limb ECG and detection of Injection on ischemic injury in rats serum creatine kinase (CPK) lactate dehydrogenase (LDH) activity and myocardial superoxide dismutase (SOD) and lipid peroxides malondialdehyde (MDA) content. Results Shenfu can reduce isoproterenol-induced ST-segment abnormalities in rats elevation, so that reduction of cardiac tissue formation of MDA, SOD activity was enhanced inhibition of the release of CPK and LDH . Conclusion Shenfu on isoproterenol induced myocardial ischemia has a protective effect, the mechanism may be related to inhibition of lipid peroxidation, increased SOD activity, reduced enzyme related. [Keywords:] injection, myocardial ischemia, rat Abstract: Objective To observe the protective effects of Shenfu injection on Isoprenaline caused by myocardal ischemia injury in rats. Methods The myocardial ischemia injury model was established by 20mg/kg of isoproterenol in rats.ECG was recorded by BL 420.The activities of serum lactate dehdrogenase and creatine phosphor kinase, the enzyme activities of superoxide dismutase, and levels of malondialdehyde content of myocardium were all measured. Results Shenfu injection significantly inhibited the elevation of ST period, significantly reduced myocardial MDA content, significantly increased myocardial SOD activity and significantly depressed the release of CPK and LDH in the rat heart with isoprenaline induced injury.Conclusion Shenfu injection exerted protective effects on ischemic myocardium injury, which might be related to the inhibition of lipidperoxidation, the enhancement of SOD activity and decrease of myocardial enzyme. Keywords:: shenfu injection, myocardial ischemial injury, rats Recent studies have found that Shenfu cardiovascular d