New type of resistance gene dissemination components- ISCR.doc

 PAGE \* MERGEFORMAT 3 New type of resistance gene dissemination components: ISCR [Abstract] With the widespread use and misuse of antibiotics, bacterial resistance to a growing problem. Transposon and integron genes could explain most of the resistance movement of DNA molecules, but they can not explain the essence and movement of resistance genes resistance genes subspecies growth. This article describes a class of spread of resistance gene components - ISCR, and to clarify the substance of widespread antibiotic resistance genes. By drawing on the results of research at home and abroad in recent years, outlined the ISCR factor and the relationship between various types of antibiotic resistance genes, and this resistance gene dissemination of research has certain significance. [Keywords:] insertion sequence (IS); common region (CR); resistance gene ABSTRACT With the widespread using of antibiotic, the issue of antibiotic resistance become more and more serious gradually. Transposon and integron systems can interpret most of the movement of resistance genes between DNA molecules, but they fail to reveal the spread of a substantial and growing subset of resistance genes. In this paper, a spread element of antibiotic resistance genes: ISCR element is introduced, and the nature of the widespread of antibiotic resistance genes is illuminated. With the research in last few years, the relationship come out between antibiotic resistance genes and ISCR elements. This will play a positive role in the aspect of spread of antibiotic genes. KEY WORDS IS; CR; Resistance genes Bacterial resistance to antibiotics once again become a hot clinical and scientific research. New ‘super-bacteria’ in the clinical treatment of recurrent, showing the form of bacterial resistance to changing the amazing ability to adapt to environmental change [1]. Bacteria have a powerful tool to adapt to changes in cell gene genetic information, this ‘genetic tool box’ and than in the past, with