Ning Chang Decoction on irritable bowel syndrome on antioxidant capacity of rats_0.doc

 PAGE \* MERGEFORMAT 13 Ning Chang Decoction on irritable bowel syndrome on antioxidant capacity of rats [Abstract] Objective To study the stress induced by irritable bowel syndrome (IBS) changes in antioxidant capacity rats and Ning Chang Decoction on the regulating role of oxygen free radicals. Methods The rats were randomly divided into 6 groups: normal group, model group, positive control group and Ning Chang Tang high, medium and low-dose group to the end of chronic stimulation of bound + folder as the original stress induced rat model of IBS. the normal group, model group were given normal saline group were given different doses of medicine Ning Chang Tang liquid gavage, the positive control group were fed pinaverium bromide solution, a total of 4 weeks. determination of malondialdehyde in rats (MDA) content and superoxide dismutase (SOD), total antioxidant capacity (T -AOC) activity, view Chaning IBS rat intestine soup on the regulation of anti-free radical oxidation effect. Results bondage + clip the end of chronic stimulation of IBS decreased antioxidant capacity in rats, serum MDA levels increased, SOD, T-AOC activity lower (P lt;0.05 ~ 0.01). Ning Chang soup can reduce IBS serum MDA, increased serum SOD, T-AOC activity (P lt;0.05 ~ 0.01). Conclusion Ning Chang Tang can increase the antioxidant capacity of rats IBS . [Keywords:] Ning Chang Tang, stress, irritable bowel syndrome, free radicals, rat Irritable bowel syndrome (irritable bowel syndrome, IBS) is a group, including abdominal pain, abdominal distension, abnormal bowel habits and stool, sustainable existence or intermittent seizures, but the lack of significant morphological and biochemical abnormalities could explain the syndrome group, its etiology and pathogenesis is not fully understood. National survey showed: IBS patients accounted for 30% of outpatient Department of Gastroenterology, 50%, consistent with the Rome Ⅱ criteria in Beijing and manning standards for the detection ra