P300 sub-components of the Research and Development.docVIP

 PAGE \* MERGEFORMAT 16 P300 sub-components of the Research and Development Keywords:: P300 sub-components P300 is the event-related potentials (ERP) based on the peak latency of around 300ms late positive wave, for the signal processing of specific potential, is a brain evoked potential study of an important discovery. At present the medical profession are concerned about the target. Sutton was the first time since 1965, has been found in P300. Carried out a large number of people of their research, initially found it with cognitive processes. Because cognitive impairment and related diseases, P300 amplitude and latency of the corresponding changes occurring in the psychological test, P300 changes in psychological tests than other indicators (such as the MMSE) occurred much earlier and therefore be used clinically, as a recognition dysfunction known as a supplementary means. In order to make detection of P300 in clinical work, to play a greater role, such as the location for diagnosis of brain injury and brain force of some advanced features of the study, people to build a variety of animal models used in audio, visual, somatosensory stimulation and other methods, the neural origin of P300 were discussed. From the discovery of P300, after almost 10 years later, people are the P300 as a separate component to study with in-depth study in 1975, Spuires other formal P300 can be divided into P3a and P3b two components, they represent different neural activities, have different distribution and the incubation period and even have their own separate neural origin. This article will at home and abroad over the past decade in the P300 sub-components of the research progress made in a review. 1 P3a and P3b evoked methods, distribution and significance of Spuires such as the probability of the target using three different sound stimulation evoked P3a was found that the probability of P300-dependent, that is, 10% of the target stimulus tone P3a amplitude induced by th