RP-HPLC determination of ipratropium bromide inhalation solution with the content of.docVIP

 PAGE \* MERGEFORMAT 13 RP-HPLC determination of ipratropium bromide inhalation solution with the content of Author: Lu Lai-Chun, Zhang Rong, Liu Tong-hua, JIANG Xue-wen 【Abstract】 Objective: RP-HPLC determination of ipratropium bromide inhalation solution with the content. Methods: The column was phenomenex  C8 (4.6 mm × 250 mm, 5 μm), mobile phase of acetonitrile  0.25% sodium n-heptane solution (29:71) with phosphoric acid adjusted pH value to 3.2; detection wavelength was 210 nm; a flow rate of 1.0 mL / min; injection volume 20 μL . Results: Ipratropium bromide in