Safflower injection adverse reactions.doc

 PAGE \* MERGEFORMAT 12 Safflower injection adverse reactions [Keywords:] safflower injection;,, adverse reactions;,, drug eruption fever;,, anaphylactic shock;, and acute renal failure syndrome Keywords:: Safflower injection; adverse reaction; eruption fever; anaphylactic shock; acute renal failure syndrome, Safflower safflower injection of Compositae processed extract of Chinese medicine preparations, yellow-red or brownish red, with blood stasis effect. Pharmacological experiments show that safflower injection can increase coronary blood flow and myocardial nutritional blood flow can be directly or partially block α -adrenergic receptor in blood vessels to expand, to effectively expand blood vessels, and reduce serum total cholesterol, total ester, 3 glyceryl trinitrate and esterification of fatty acids and anti-thrombosis and platelet aggregation; may protect against brain tissue and the analgesic, sedative, anti-convulsion, anti-inflammatory, excitement, uterus, smooth muscle excitatory effect; can improve cell hypoxic state and the homeostasis of liver and other organs to increase heart and brain blood flow, improve microcirculation. For the treatment of occlusive cerebrovascular disease, coronary heart disease and other diseases. With the increasing clinical application, safflower injection adverse reactions have also been reported. In this paper, in recent years, adverse reactions reported in the literature are reviewed in order to pay attention to. A drug eruption Nan-Tsing Chiu [1] reported four cases were in patients with chronic renal insufficiency, including 3 males and 1 female, aged 25 to 57 years. Given 5% glucose 250 ml, safflower injection 20 ml, intravenous drip. 2 ~ 3d after drug rash, hand, foot and back before now, there is 1 case gradually spread to the trunk and head and face, rash prominent leather, the pressure of the non-fading, accompanied by itching. Subsequently suspended safflower injection, severe local itching to give Pi Ya