The pharmacological effects of PNS Progress.docVIP

 PAGE \* MERGEFORMAT 30 The pharmacological effects of PNS Progress 【Abstract】 Objective To review the pharmacological effects of PNS are reviewed. Method of access to the literature, and conduct analysis, summarized and concluded. The results of PNS in the central nervous system, heart and brain vascular system, blood system, immune system and anti-fibrosis, anti-aging, anti cancer etc. broad physiological activity. Conclusion of PNS worthy of further development and application. Keywords: Panax notoginseng saponins; pharmacological effects Panax notoginseng saponins (total saponins of Panax notognseng, PNS) is the Araliaceae Panax genus 37 of the main effective active ingredient, contains a number of single saponin. 40 years beginning from the 20th century, scholars at home and abroad PNS conducted a series of studies has revealed the expansion of its blood vessels, reducing myocardial oxygen consumption, inhibit platelet aggregation and prolong clotting time, blood fat, removing free radicals, anti-inflammatory, anti - oxide and other pharmacological effects. In order to understand the situation of its latest research, the author of the PNS on the latest research advances in recent years to make a brief overview. 1 on the central nervous system effects of 1.1 Sedation 37 aerial parts of the central nervous system inhibit the expression of calm, stability and improve the function of sleep and so on. PNS can reduce the autonomy of the activities of animals, showing a marked sedative effect, and can inhibit the drug central coordination role that central inhibition is through reduction of synaptic glutamate levels to be achieved [1]. Analgesic effect of 1.2 PNS on the chemical and thermal stimulation caused by pain were significantly analgesic effect, and the PNS is an opioid-like receptor agonist, does not have the addictive side effects [2]. 1.3 Puzzle Role PNS could improve the ib